منابع مشابه
Mechanism of allyl alcohol toxicity.
the OX-19 strain. A second strain of a Proteus sp., when inoculated into infusion broth containing penicillin, also produced large bodies. None of the bodies, however, were seen to revert to rods. Filtrates of such cultures were without activity in neutralizing the effect of the antibiotic. This second organism, however, grew profusely in the rod form in a broth-penicillin mixture to which acti...
متن کاملNitric Oxide and Allyl Alcohol Induced Hepatotoxicity
Background. Nitric oxide (NO) is an important mediator of hepatotoxicity. NO in liver can be derived from two sources: (1) constitutive NO synthase (eNOS) in endothelial cells, and (2) inducible NO synthase (iNOS) in hepatocytes and Kupffer cells. Objectives. The present study was aimed to examine the effect of nonselective NOS inhibitor (L-NAME) and selective iNOS inhibitor (1400W) on the deve...
متن کاملConferring Temperature-Conditional Allyl Alcohol Resistance
Selection for allyl alcohol resistance in respiratory incompetent yeast is a highly specific method for isolating functional mutations at ADHI, the gene coding for the cytoplasmic alcohol dehydrogenase, ADHI. Because of the nature of this selection scheme, the ADHI activity of such mutants is retained, but the kinetic characteristics of the enzymes are altered. The high specificity for targetin...
متن کاملPentoxifylline attenuates bacterial lipopolysaccharide-induced enhancement of allyl alcohol hepatotoxicity.
Small amounts of exogenous lipopolysaccharide (LPS) (10 ng/kg-100 microg/kg) enhance the hepatotoxicity of allyl alcohol in male Sprague-Dawley rats. This augmentation of allyl alcohol hepatotoxicity appears to be linked to Kupffer cell function, but the mechanism of Kupffer cell involvement is unknown. Since Kupffer cells produce tumor necrosis factor-alpha (TNF alpha) upon exposure to LPS, an...
متن کاملPalladium-diphosphine complexes as catalysts for allylations with allyl alcohol
Several palladium complexes with bidentate phosphine ligands were tested for their activity in the O-allylation of phenols with allyl alcohol. The use of C3-bridged bidentate phosphine ligands results in very high selectivity for O-allylation. The reactions do not require stoichiometric amounts of additives to control the chemoselectivity. Especially, catalysts with gem-dialkyl substituted C3-b...
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ژورنال
عنوان ژورنال: Journal of Synthetic Organic Chemistry, Japan
سال: 1987
ISSN: 0037-9980,1883-6526
DOI: 10.5059/yukigoseikyokaishi.45.73